Selected Publications

Research Article

1. Li Y, Ding W, Li C-Y and Liu Y*. HLH-11 modulates lipid metabolism in response to nutrient availability. Nature Communications (2020) 11:5959.

2. Shao L-W#, Peng Q#, Dong M, Gao K, Li YM, Li Y, Li C-Y* and Liu Y*. Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity. Nature Communications (2020) 11(1):4639.

3. Gao K, Li Y, Hu SM and Liu Y*. SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension. eLife (2019) e41792.

4. Ma C, Niu R, Huang T, Shao LW, Peng Y, Ding W, Wang Y, Jia G, He C, Li CY, He A and Liu Y*. N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation. Nature Cell Biology (2018) DOI: 10.1038/s41556-018-0238-5.

5. Chen J, Ou Y, Yang Y, Li W, Xu Y, Xie Y and Liu Y*. KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. Nature 557(2018) 585-589.

6. Chen J#, Ou Y#, Li Y, Hu S, Shao LW and Liu Y*. Metformin extends C. elegans lifespan through lysosomal pathway. eLife 6 (2017) e31268.

7. Shao LW, Niu R and Liu Y*. Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response. Cell Res. 11 (2016) 1182-1196. (cover story)

8. Berendzen K, Durieux J, Shao L, Tian Y, Kim H, Wolff S, Liu Y and Dillin A. Neuroendocrine coordination of mitochondrial stress signaling and proteostasis. Cell 166 (2016) 1553-1563.

9. Liu Y, Samuel BS, Breen PC and Ruvkun G. Caenorhabditis elegans pathways that surveil and defend mitochondria. Nature (2014) doi:10.1038/nature13204.

10. Liu Y, Tan H, Tian H, Liang C, Chen S and Liu Q. Autoantigen La promotes efficient RNAi, antiviral response and transposon silencing by facilitating multiple-turnover RISC catalysis. Mol. Cell 44 (2011) 502-508.

11. Ye X*, Huang N*, Liu Y, Paroo Z, Huerta C, Li P, Chen S, Liu Q and Zhang H. Structure of C3PO and mechanism of Human RISC activation. Nat. Struct. Mol. Biol. 18 (2011) 650-657.

12. Liu Y, Ye X, Jiang F, Liang C, Chen D, Peng J, Kinch L, Grishin N, Liu Q. C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. Science 5941 (2009) 750-753.

Invited Review

1. Liu Y*. Epigenetic codes of mitochondrial homeostasis. Nature Aging 1 (2021) 153-154

2. Wang S, Gao K, and Liu Y*. UPRmt coordinates immunity to maintain mitochondrial homeostasis and animal fitness. Mitochondrion (2017)

3. Liu Y and Liu Q. ATM signals miRNA biogenesis through KSRP. Mol. Cell 41 (2011) 367-368